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Hal ini tergantung dari jenis gangguan kesehatan yang sedang diobati, tingkat keparahan, serta respon tubuh seseorang terhadap penggunaan obat

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albicans infection leads to a significant reduction in mucosal bacterial diversity, accompanied by the abnormal overgrowth of Enterococcus on oral and small intestinal mucosae, and the overproliferated Enterococcus can degrade the epithelial junction protein E-cadherin in vitro and in vivo , destroy the integrity of the mucosal epithelial barrier and increase its permeability

Microglia respond to local and systemic inflammatory stimuli by producing pro-inflammatory cytokines (PIC), including interleukin-1 and (IL-1 and IL-1), tumor necrosis factor (TNF-), and interleukin-6 (IL-6) (79)